Further evidence for insufficient hypothalamic-pituitary-glandular axes in polymyalgia rheumatica.
نویسندگان
چکیده
منابع مشابه
Treatment of polymyalgia rheumatica with intramuscular injections of depot methylprednisolone.
Although the treatment of patients with polymyalgia rheumatica by corticosteroids given by mouth is effective, it is often accompanied by multiple side effects. Various studies have shown that the steroid related complications are proportional to the cumulative dose of steroids administered. In a prospective study of 16 patients with polymyalgia rheumatica the effects of regular intramuscular i...
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INTRODUCTION In this study, we evaluated the activity of the neuroendocrine axes in patients with polymyalgia rheumatica (PMR) before and after tumor necrosis factor (TNF)-α-blocking etanercept treatment, which previously has been shown to reduce interleukin 6 (IL-6) and C-reactive protein (CRP) markedly in PMR. METHODS Plasma samples were collected from 10 glucocorticoid-naïve patients with ...
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Glucocorticoids are the mainstay of treatment in patients with polymyalgia rheumatica (PMR). Moreover, lower serum cortisol levels have been reported in patients with PMR, suggesting an important role of impaired hypothalamus-pituitary-adrenal (HPA) axis in the pathogenesis of the disease. Therefore, a good response to glucocorticoids has been recognised as a feature of PMR, even if disagreemen...
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Polymyalgia rheumatica and rheumatoid arthritis may be difficult to differentiate in elderly patients. Polymyalgic symptoms are common in the prodromal phase of rheumatoid arthritis and, as specific diagnostic tests do not exist for either condition, criteria for diagnosis of the diseases are based largely on clinical features. I2 The presence ofsynovitis similar to rheumatoid arthritis in some...
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عنوان ژورنال:
- The Journal of rheumatology
دوره 33 7 شماره
صفحات -
تاریخ انتشار 2006